Aldol elaboration of 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridin-4-ones, masked precursors to acylpyridones
| Autor: | Mark E. Light, Abdul K. Choudhury, Raymond C. F. Jones, Terence A. Pillainayagam, Jim Iley, Georgia Loizou |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
heterocycles
Metalation Organic Chemistry isoxazole metalation pyridone Full Research Paper fused-ring systems lcsh:QD241-441 Chemistry chemistry.chemical_compound Aldol reaction chemistry lcsh:Organic chemistry Organic chemistry aldol reaction Aldol condensation lcsh:Q Isoxazole lcsh:Science Elaboration |
| Zdroj: | Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 308-312 (2012) Beilstein Journal of Organic Chemistry |
| ISSN: | 1860-5397 |
| Popis: | A core 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-one scaffold is elaborated at C-3(Me) by base-mediated aldol condensation to give new 3-alkenyl-4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-ones, which are masked forms related to the acylpyridone natural products. |
| Databáze: | OpenAIRE |
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