Lewis acid catalysis: regioselective hydroboration of alkynes and alkenes promoted by scandium triflate
| Autor: | K. Geetharani, Piyush Kumar Verma, Souvik Mandal |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
010405 organic chemistry
Metals and Alloys chemistry.chemical_element Regioselectivity General Chemistry 010402 general chemistry Metathesis 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Lewis acid catalysis Hydroboration chemistry Materials Chemistry Ceramics and Composites Side chain Scandium Trifluoromethanesulfonate |
| Zdroj: | Chemical communications (Cambridge, England). 54(97) |
| ISSN: | 1364-548X |
| Popis: | The first commercially available scandium-catalysed selective hydroboration of alkynes and alkenes with HBpin (pin = OC-Me2CMe2O) in the presence of a catalytic amount of NaHBEt3 has been developed. This protocol can be applicable to a wide range of substrates including aromatic, aliphatic with cyclic and acyclic side chains, and heteroaryl systems with broad functional-group compatibility. Mechanistic studies revealed that the reaction occurs in a syn fashion via the σ-bond metathesis between the alkenyl scandium species and HBpin. |
| Databáze: | OpenAIRE |
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