Latent tuberculosis infection screening in persons newly-diagnosed with HIV infection in Italy: a multicentre study promoted by the Italian Society of Infectious and Tropical Diseases
| Autor: | Claudio Maria Mastroianni, Mirko Compagno, Nicoletta Orchi, Assunta Navarra, Gabriella De Carli, Andrea Calcagno, Daniela Piacentini, Claudia Cimaglia, Delia Goletti, Gilda Cuzzi, Veronica Pirriatore, Loredana Sarmati, Elisa Petruccioli, Andrea Antinori, Laura Fondaco, Fabio Franzetti, Paolo Pavone, Alberto Giannetti, Valentina Mazzotta, Evelina Tacconelli, Miriam Lichtner, Andrea Gori, Giuseppe Lapadula, Enrico Girardi, Massimo Galli, Anna Spolti, Emanuele Pontali |
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| Přispěvatelé: | Goletti, D, Navarra, A, Petruccioli, E, Cimaglia, C, Compagno, M, Cuzzi, G, De Carli, G, Fondaco, L, Franzetti, F, Giannetti, A, Gori, A, Lapadula, G, Lichtner, M, Mastroianni, C, Mazzotta, V, Orchi, N, Pavone, P, Piacentini, D, Pirriatore, V, Pontali, E, Sarmati, L, Spolti, A, Tacconelli, E, Galli, M, Antinori, A, Calcagno, A, Girardi, E |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male Interferon gamma release assay HIV Infections Sexual and Gender Minorities Sexual and Gender Minoritie 0302 clinical medicine Retrospective Studie Medicine Infection control Mass Screening HIV Infection 030212 general & internal medicine ltbi active tb cd4 t-cells hiv igra latency quantiferon tuberculosis Latent Tuberculosi IGRA Latent tuberculosis General Medicine Middle Aged Infectious Diseases Italy CD4 T-cell Female Human Microbiology (medical) Adult medicine.medical_specialty Tuberculosis Settore MED/17 - Malattie Infettive Tuberculosi 030106 microbiology QuantiFERON 03 medical and health sciences Active TB CD4 T-cells HIV Latency LTBI Quantiferon CD4 Lymphocyte Count Humans Latent Tuberculosis Retrospective Studies Tuberculin Test Internal medicine Latent tuberculosis infection screening Risk factor Mass screening business.industry Odds ratio bacterial infections and mycoses medicine.disease business |
| Popis: | Background: The Italian Society of Infectious and Tropical Diseases performed a survey on the application of guidelines for the management of persons living with HIV (PLWH), to evaluate current practice and the yield of screening for latent tuberculosis infection (LTBI) in newly-diagnosed PLWH; in addition, the offer of preventive therapy to LTBI individuals and the completion rate were analysed. Materials and methods: Newly-diagnosed PLWH in nine centres were evaluated retrospectively (2016/2017) using binary and multinomial logistic regression to identify factors associated with LTBI diagnostic screening and QuantiFERON (QFT) results. Results: Of 801 patients evaluated, 774 were studied after excluding active TB. LTBI tests were performed in 65.5%. Prescription of an LTBI test was associated with being foreign-born (odds ratio (OR) 3.19, p < 0.001), older (for 10-year increments, OR 1.22, p = 0.034), and having a CD4 count |
| Databáze: | OpenAIRE |
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