Microbubble-mediated intravascular ultrasound imaging and drug delivery
| Autor: | Johnny L. Chen, Adam J. Dixon, Joseph P. Kilroy, Michael Ragosta, John A. Hossack, Alexander L. Klibanov, Brian R. Wamhoff, Ali H. Dhanaliwala, Linsey C. Phillips |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Molecular composition Acoustics and Ultrasonics Swine Drug Delivery Systems Intravascular ultrasound Medicine Animals Humans cardiovascular diseases Electrical and Electronic Engineering Image guidance Instrumentation Ultrasonography Interventional Microbubbles medicine.diagnostic_test business.industry Atherosclerotic disease equipment and supplies surgical procedures operative Carotid Arteries Drug delivery cardiovascular system Imaging technology Radiology Rabbits Molecular imaging business Biomedical engineering |
| Zdroj: | IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 62(9) |
| ISSN: | 1525-8955 |
| Popis: | Intravascular ultrasound (IVUS) provides radiation-free, real-time imaging and assessment of atherosclerotic disease in terms of anatomical, functional, and molecular composition. The primary clinical applications of IVUS imaging include assessment of luminal plaque volume and real-time image guidance for stent placement. When paired with microbubble contrast agents, IVUS technology may be extended to provide nonlinear imaging, molecular imaging, and therapeutic delivery modes. In this review, we discuss the development of emerging imaging and therapeutic applications that are enabled by the combination of IVUS imaging technology and microbubble contrast agents. |
| Databáze: | OpenAIRE |
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