Intracytoplasmic sperm injection (ICSI) and chromosomally abnormal spermatozoa
| Autor: | P. A. In't Veld, F. J. Broekmans, H. F. de France, P. L. Pearson, M. H. Pieters, R. J. van Kooij |
|---|---|
| Přispěvatelé: | Clinical Genetics, Obstetrics & Gynecology |
| Rok vydání: | 1997 |
| Předmět: |
Teratospermia
Adult Male Cytoplasm Genotype Microinjections medicine.medical_treatment Aneuploidy Chromosome Disorders Fertilization in Vitro Biology Intracytoplasmic sperm injection Male infertility Andrology medicine Humans reproductive and urinary physiology In Situ Hybridization Fluorescence Infertility Male Azoospermia Chromosome Aberrations Sperm-Ovum Interactions urogenital system Rehabilitation Obstetrics and Gynecology Oligospermia medicine.disease Sperm Phenotype Reproductive Medicine Female medicine.symptom |
| Zdroj: | Human Reproduction, 12(4), 752-754. Oxford University Press |
| ISSN: | 1460-2350 0268-1161 |
| DOI: | 10.1093/humrep/12.4.752 |
| Popis: | An infertile couple was referred for intracytoplasmic sperm injection (ICSI) because of primary infertility and oligoasthenoteratozoospermia (OAT) in the male. It was observed that although the sperm cells presented with an unusual head size and multiple tails they were able to fertilize the oocytes after ICSI. Subsequent molecular cytogenetic analysis demonstrated de-novo chromosome abnormalities in virtually all sperm cells with 40% diploidy and 24% triploidy in addition to aneuploidy for the sex chromosomes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|