Ring-Opening/Recyclization Cascades of Monoactivated Cyclopropanes

Autor:	Uttam K. Mishra, S. S. V. Ramasastry, Kaushalendra Patel
Rok vydání:	2020
Předmět:	010405 organic chemistry Stereochemistry Aryl Organic Chemistry Substituent 010402 general chemistry Ring (chemistry) 01 natural sciences Biochemistry Product distribution 0104 chemical sciences Stereocenter chemistry.chemical_compound chemistry Physical and Theoretical Chemistry
Zdroj:	Organic Letters. 22:3815-3819
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.0c01056
Popis:	A variety of cyclopropyl aryl ketones undergo uncatalyzed cascade ring-opening/recyclization reactions to generate indenones and fluorenones. In addition, a new strategy to access 3-hydroxyindanones possessing two contiguous stereogenic centers, one of them being an all-carbon quaternary center, was also established. During the course of the investigation, pronounced solvent, temperature, and substituent effects on the product distribution were discovered.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f62256487185809ded34fde41ed2e5 https://doi.org/10.1021/acs.orglett.0c01056 Zobrazit plný text záznamu