Functional Swallowing Units (FSUs) as organs-at-risk for radiotherapy. PART 1
| Autor: | Jan Wedman, Monique Holwerda, Anton M van der Vliet, Max J. H. Witjes, A. Gawryszuk, Johannes A. Langendijk, Bart Dorgelo, Hendrik P. Bijl, Gyorgy B. Halmos |
|---|---|
| Přispěvatelé: | Guided Treatment in Optimal Selected Cancer Patients (GUTS), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Larynx
Organs at Risk Physiology 030218 nuclear medicine & medical imaging Pharyngeal muscles 03 medical and health sciences 0302 clinical medicine Swallowing Tongue medicine otorhinolaryngologic diseases Humans Radiology Nuclear Medicine and imaging Genioglossus business.industry Radiotherapy Planning Computer-Assisted digestive oral and skin physiology Hematology Anatomy Dysphagia Hyoglossus Deglutition medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Styloglossus Pharyngeal Muscles medicine.symptom Laryngeal Muscles business Deglutition Disorders |
| Zdroj: | Radiotherapy and Oncology, 130, 62-67. ELSEVIER IRELAND LTD |
| ISSN: | 1879-0887 0167-8140 |
| DOI: | 10.1016/j.radonc.2018.10.028 |
| Popis: | BACKGROUND AND PURPOSE: When optimising radiotherapy treatments today, the pharyngeal constrictor muscles and the larynx are usually regarded as the swallowing organs at risk (SWOARs). The purpose of this study was to identify and describe additional, previously undefined groups of muscles (functional units) involved in crucial components of swallowing (hyolaryngeal elevation (HLE), tongue base retraction (TBR) and tongue motion), and to emphasise their relevance in radiation-induced dysphagia.MATERIAL AND METHODS: Based on available literature on human anatomy and swallowing physiology, the functional units of muscles involved in HLE, TBR and tongue motion have been identified and described.RESULTS AND CONCLUSION: Functional swallowing units (FSUs) were defined as groups of swallowing muscles sharing their function, that are in close proximity to each other. Seven FSUs involved in HLE, TBR and tongue motion were identified: floor of mouth, thyrohyoid muscles, posterior digastric/stylohyoid muscles complex, longitudinal pharyngeal muscles, hyoglossus/styloglossus muscles complex, genioglossus muscles, intrinsic tongue muscles. The swallowing physiology and anatomy of the FSUs described in this paper will lead to a greater understanding of radiation-induced dysphagia mechanisms and, consequently, to an improvement in the development of swallowing sparing strategies. This article (PART 1) serves as the theoretical foundation for a subsequent article (PART 2), which provides detailed delineation guidelines for FSUs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect