Factors affecting survival after excision of the rectum for cancer

Autor: Owen F. Dent, Peter Stewart, P. Zelas, S. G. Koorey, R. C. Newland, Pierre H. Chapuis, E. L. Bokey
Rok vydání: 1997
Předmět:
Zdroj: Diseases of the Colon & Rectum. 40:3-10
ISSN: 0012-3706
DOI: 10.1007/bf02055674
Popis: PURPOSE: The aim of this study was to identify and categorize the independent prognostic effects of patient, clinical, operative, and pathology variables on long-term survival after anterior resection or abdominoperineal excision of the rectum for cancer. METHODS: Proportional hazards regression analysis was used to analyze prospective data from 709 patients who underwent surgery at Concord Hospital during a 23-year period. No patient received adjuvant therapy. RESULTS AND CONCLUSIONS: After adjusting for age and clinicopathologic stage, significantly poorer survival was experienced by males, patients with extensive tumor adherent to other organ(s), those with a high-grade tumor or a tumor showing venous invasion, those who had a postoperative cardiovascular or respiratory complication, and those who did not undergo surgery by a colorectal surgeon specialist. The nature of the operation performed had no independent effect on survival.
Databáze: OpenAIRE