Sexual Dysfunction in a Patient Taking Ledipasvir/Sofosbuvir for the Treatment of Hepatitis C: A Case Report
| Autor: | Effie L. Crutcher, Elisa Greene, Destin U. Lenz |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Ledipasvir
Adult Male Pediatrics medicine.medical_specialty Sofosbuvir Side effect Drug-Related Side Effects and Adverse Reactions Hepatitis C virus medicine.disease_cause 030226 pharmacology & pharmacy Antiviral Agents 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine Humans Pharmacology (medical) 030212 general & internal medicine Hepatitis Fluorenes business.industry Hepatitis C medicine.disease Discontinuation Sexual Dysfunction Physiological Sexual dysfunction chemistry Benzimidazoles medicine.symptom business Uridine Monophosphate medicine.drug |
| Zdroj: | Journal of pharmacy practice. 32(2) |
| ISSN: | 1531-1937 |
| Popis: | Sexual dysfunction is a bothersome side effect of several medications, though it has not yet been reported with the use of ledipasvir/sofosbuvir for the treatment of hepatitis C. However, sexual dysfunction is a potentially unrecognized side effect of ledipasvir/sofosbuvir that could result in nonadherence and treatment failure. We report a case of a 42-year-old man with a sudden onset of sexual dysfunction with the initiation of ledipasvir/sofosbuvir for the treatment of hepatitis C. The patient had no prior history or risk factors for the development of sexual dysfunction. His symptoms resolved upon discontinuation of ledipasvir/sofosbuvir after a successful 12-week course. Clinicians should be aware that sexual dysfunction is a possible side effect of ledipasvir/sofosbuvir and educate patients appropriately. Adherence should be emphasized as the risks of untreated hepatitis C virus far outweigh transient sexual dysfunction. |
| Databáze: | OpenAIRE |
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