Changing uveitis patterns in South India - Comparison between two decades
| Autor: | Priyansha Multani, Jyotirmay Biswas, Ranju Kharel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Tuberculosis 030106 microbiology Population Retinitis Eye Infections Viral India Uveitis 03 medical and health sciences Young Adult 0302 clinical medicine lcsh:Ophthalmology Ophthalmology medicine Prevalence Humans education Toxoplasmosis Ocular Tuberculosis Pulmonary Changing pattern Retrospective Studies education.field_of_study business.industry Incidence (epidemiology) South India Incidence Panuveitis medicine.disease Toxoplasmosis tuberculosis lcsh:RE1-994 030221 ophthalmology & optometry Intermediate uveitis Original Article Female business toxoplasmosis |
| Zdroj: | Indian Journal of Ophthalmology Indian Journal of Ophthalmology, Vol 66, Iss 4, Pp 524-527 (2018) |
| ISSN: | 1998-3689 0301-4738 |
| Popis: | Purpose: Changing pattern of uveitis in a subset of a population is an important ocular health indicator. Methods: A comparative study was done between uveitis patients of 2013 and 1995 using two proportions Z-test. Results: In 2013, 352 new uveitis cases were examined. Males 56%, females 44%; unilateral 30.4%; bilateral in 69.6%. A specific diagnosis achieved in 66.2%. Anterior uveitis was seen in 35.22%, intermediate uveitis in 30.11%, posterior uveitis in 25%, and panuveitis in 9.65%. There was no significant difference in the incidence of new uveitic cases (1.04% vs. 1.8%). A decline in male preponderance from 64% to 56% (P = 0.0187) was observed. In both studies, anterior uveitis was the most common but human leukocyte antigen-B27 positivity uveitis had increased (29.83% vs. 14.5%; P < 0.05). Intermediate uveitis was the second-most common type instead of posterior uveitis (P = 0.0006). In posterior uveitis cases, etiology was established in 88.6% versus 56.06% cases (P < 0.05). The most common cause of posterior uveitis was tuberculosis (TB) (35.2%). Viral retinitis had increased to 6.81% from 0.76% (P < 0.05). However, a declining trend in cases of toxoplasmosis was observed (P = 0.0545). The cause of panuveitis was comparable in both studies. The prevalence of TB has significantly increased in the present era (22.5% vs. 0.64%; P < 0.0001) and was the proven etiological cause of uveitis in overall 22.5% of which 4.8% cases were of anterior uveitis cases, 7.1% cases of intermediate uveitis cases, 8.8% cases of posterior uveitis cases, and 1.8% of panuveitis cases. Conclusion: A shifting paradigm of uveitis over the past two decades was observed. |
| Databáze: | OpenAIRE |
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