| Autor: |
EW Alton, D Currie, R Logan-Sinclair, JO Warner, ME Hodson, DM Geddes |
| Rok vydání: |
1990 |
| Předmět: |
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| Zdroj: |
The European respiratory journal. 3(8) |
| ISSN: |
0903-1936 |
| Popis: |
Patients with cystic fibrosis (CF) demonstrate a markedly more negative potential difference (PD) across respiratory epithelia than normal or "diseased" controls. A technique is described for the measurement of nasal PD in both children and adults. 145 non-CF subjects showed a mean PD of -19.0 mV (range -2 to -36) in comparison to 60 patients with cystic fibrosis with mean of -46.0 mV (range -32 to -77). Amongst the latter group those with more severe disease had a more negative PD. Measurement of nasal PD is easily learnt and rapidly performed and may provide an additional means of diagnosis for CF. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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