Treatment with a Direct Oral Anticoagulant for Nonbacterial Thrombotic Endocarditis

Autor: Masa-aki Kawashiri, Soichiro Usui, Masayuki Takamura, Yudai Tamura, Kenji Sakata, Kazushi Terada
Rok vydání: 2021
Předmět:
medicine.medical_specialty
Lung Neoplasms
Deep vein
medicine.medical_treatment
Case Report
030204 cardiovascular system & hematology
Nonbacterial thrombotic endocarditis
direct oral anticoagulants
culture-negative endocarditis
03 medical and health sciences
0302 clinical medicine
Internal Medicine
medicine
Humans
echocardiography
Embolization
Letters to the Editor
Lung cancer
postmortem
Lung
Endocarditis
business.industry
valvular heart disease
Anticoagulants
Cerebral Infarction
General Medicine
Middle Aged
medicine.disease
Thrombosis
Surgery
lupus anticoagulant-hypoprothrombinemia syndrome
lung cancer
medicine.anatomical_structure
Coxiella burnetii
Endocarditis
Non-Infective

Bartonella species
Patent foramen ovale
Female
nonbacterial thrombotic endocarditis
030211 gastroenterology & hepatology
business
Zdroj: Internal Medicine
ISSN: 1349-7235
0918-2918
Popis: We herein report a case of nonbacterial thrombotic endocarditis (NBTE) in a patient with previously undiagnosed lung cancer. A 62-year-old woman presented to our hospital with multiple cerebral infarctions. There was no evidence of valvular heart disease or vegetations. Whole-leg ultrasonography revealed deep vein thrombosis of the left peroneal vein. We administered direct oral anticoagulants (DOACs) for a presumed diagnosis of paradoxical embolisms caused by patent foramen ovale. Unfortunately, she experienced further embolization and died. At a postmortem examination, she was diagnosed with NBTE and metastatic adenocarcinoma of the lung. Our experience with this patient suggests that DOACs may be an insufficient treatment for NBTE.
Databáze: OpenAIRE