Treatment with a Direct Oral Anticoagulant for Nonbacterial Thrombotic Endocarditis
| Autor: | Masa-aki Kawashiri, Soichiro Usui, Masayuki Takamura, Yudai Tamura, Kenji Sakata, Kazushi Terada |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Lung Neoplasms Deep vein medicine.medical_treatment Case Report 030204 cardiovascular system & hematology Nonbacterial thrombotic endocarditis direct oral anticoagulants culture-negative endocarditis 03 medical and health sciences 0302 clinical medicine Internal Medicine medicine Humans echocardiography Embolization Letters to the Editor Lung cancer postmortem Lung Endocarditis business.industry valvular heart disease Anticoagulants Cerebral Infarction General Medicine Middle Aged medicine.disease Thrombosis Surgery lupus anticoagulant-hypoprothrombinemia syndrome lung cancer medicine.anatomical_structure Coxiella burnetii Endocarditis Non-Infective Bartonella species Patent foramen ovale Female nonbacterial thrombotic endocarditis 030211 gastroenterology & hepatology business |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.6368-20 |
| Popis: | We herein report a case of nonbacterial thrombotic endocarditis (NBTE) in a patient with previously undiagnosed lung cancer. A 62-year-old woman presented to our hospital with multiple cerebral infarctions. There was no evidence of valvular heart disease or vegetations. Whole-leg ultrasonography revealed deep vein thrombosis of the left peroneal vein. We administered direct oral anticoagulants (DOACs) for a presumed diagnosis of paradoxical embolisms caused by patent foramen ovale. Unfortunately, she experienced further embolization and died. At a postmortem examination, she was diagnosed with NBTE and metastatic adenocarcinoma of the lung. Our experience with this patient suggests that DOACs may be an insufficient treatment for NBTE. |
| Databáze: | OpenAIRE |
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