A Double-Blind Study of the Therapeutic Efficacy of Zinc Gluconate on Taste Disorder
| Autor: | Hiroshi Tomita, Souhei Endo, Shinya Yoshida |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Taste Erythrocytes Administration Oral chemistry.chemical_element Zinc Pharmacology Placebo Gluconates Severity of Illness Index Gastroenterology law.invention Double blind study Taste Disorders Double-Blind Method Randomized controlled trial law Internal medicine Severity of illness medicine Humans business.industry General Medicine Middle Aged Clinical trial Otorhinolaryngology chemistry Taste disorder Female Surgery business |
| Zdroj: | Auris Nasus Larynx. 18:153-161 |
| ISSN: | 0385-8146 |
| Popis: | The therapeutic efficacy of orally given zinc gluconate on taste disorder was investigated by a double-blind study in 98 patients with a chief complaint of this disease. The subjects were divided into two 49-patient groups and were orally given zinc gluconate or the placebo for up to 4 months. Improvement of taste examination and subjective symptoms was analyzed in 65 of the subjects. Although no significant difference was detected between the two groups in overall efficacy, a significant superiority of zinc gluconate to placebo was observed in patients with idiopathic and zinc-deficient taste disorder. Comparison of the improvement by Ridit analysis showed a significant therapeutic superiority of zinc gluconate. In contrast, comparison of the degree of subjective symptomatic changes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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