Histiocytic medullary reticulosis
Autor: | Emanuel Rubin, Frederick G. Zak |
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Rok vydání: | 1961 |
Předmět: |
Leukemia
Hairy Cell Pathology medicine.medical_specialty Medullary cavity business.industry Hepatosplenomegaly Genetic Diseases X-Linked Spleen General Medicine Erythrophagocytosis Medical Records medicine.anatomical_structure Immunology medicine Severe Combined Immunodeficiency Bone marrow Lymph medicine.symptom business Lymphatic Diseases Lymph node Histiocyte |
Zdroj: | The American Journal of Medicine. 31:813-819 |
ISSN: | 0002-9343 |
Popis: | The case presented fulfills the clinical and morphologic requirements of histiocytic medullary reticulosis as laid down by Bodley Scott and Robb-Smith [1]. This invariably and apparently rapidly fatal disease of adults is characterized morphologically by a diffuse proliferation of phagocytic histiocytes and their precursors in lymph nodes, spleen, liver, bone marrow and other organs. The striking erythrophagocytosis, particularly in the spleen, is diagnostic. Wasting, fever, moderate lymph node enlargement, hepatosplenomegaly, hypersplenism and icterus are found. |
Databáze: | OpenAIRE |
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