Hospital-based surveillance to estimate the burden of rotavirus gastroenteritis among European children younger than 5 years of age

Autor: Forster, Johannes, Guarino, Alfredo, Parez, Nathalie, Moraga, Fernando, Román, Enriqueta, Mory, Olivier, Tozzi, Alberto E, De Aguileta, Ana López, Wahn, Ulrich, Graham, Clive, Berner, Reinhard, Ninan, Titus, Barberousse, Celia, Meyer, Nadia, Soriano-Gabarró, Montse, Renseigné, Non
Přispěvatelé: Children's Hospital, St. Josefskrankenhaus, Université Pierre et Marie Curie - Paris 6 (UPMC), Department for Pediatric Pneumology and Immunology, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Forster, J, Guarino, Alfredo, Parez, N, Moraga, F, Roman, E, Mory, O, Tozzi, Ae, de Aguileta, Al, Wahn, U, Graham, C, Berner, R, Ninan, T, Barberousse, C, Meyer, N, Soriano gabarrò, M, the Rotavirus Study, Group
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Pediatrics
Pediatrics, American Academy of Pediatrics, 2009, 123 ((3)), pp.e393-400. ⟨10.1542/peds.2008-2088⟩
Pediatrics, 2009, 123 ((3)), pp.e393-400. ⟨10.1542/peds.2008-2088⟩
ISSN: 0031-4005
1098-4275
DOI: 10.1542/peds.2008-2088⟩
Popis: OBJECTIVES. Rotavirus is the leading cause of acute gastroenteritis requiring hospitalization in young children. Data on the burden of rotavirus gastroenteritis are needed to guide recommendations for rotavirus vaccine use. This study was undertaken to estimate the burden of rotavirus gastroenteritis in European children METHODS. This prospective, study was conducted in 12 hospitals in France, Germany, Italy, Spain, and the United Kingdom. A sample of all children aged RESULTS. Between February 2005 and August 2006, 3734 children with community-acquired acute gastroenteritis were recruited and retained for analysis (55.9% via the emergency department, 41.8% hospitalized). Of the 2928 community-acquired acute gastroenteritis cases for which stool samples were available, 43.4% were rotavirus-positive by enzyme-linked immunosorbent assay (32.8% emergency department, 56.2% hospitalized). Of these rotavirus gastroenteritis cases 80.9% occurred in children aged CONCLUSIONS. Rotavirus gastroenteritis places high demands on European health care systems, accounting for 56.2% of hospitalizations and 32.8% of emergency department visits because of community-acquired acute gastroenteritis in children aged
Databáze: OpenAIRE