Long term prognostic benefit of complete revascularization in elderly presenting with NSTEMI: real world evidence
| Autor: | Brais Díaz, Alberto Cordero, Rosa Agra-Bermejo, Leyre Álvarez Rodríguez, Diego Iglesias Álvarez, Pedro Rigueiro Veloso, Belén Cid Álvarez, Charigan Abou-Jokh, José Ramón González-Juanatey, José María García Acuña, Belén Álvarez Álvarez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Population Coronary Artery Disease Revascularization Real world evidence Culprit elderly Percutaneous Coronary Intervention Internal medicine Myocardial Revascularization medicine Humans Diseases of the circulatory (Cardiovascular) system Myocardial infarction Non-ST Elevated Myocardial Infarction education Aged Retrospective Studies education.field_of_study business.industry Retrospective cohort study General Medicine Prognosis medicine.disease mortality humanities Treatment Outcome RC666-701 Propensity score matching Cardiology ST Elevation Myocardial Infarction Population study revascularization Cardiology and Cardiovascular Medicine business |
| Zdroj: | Reviews in Cardiovascular Medicine, Vol 22, Iss 2, Pp 475-482 (2021) |
| ISSN: | 2153-8174 |
| Popis: | The benefit of complete revascularization in elderly patients with non-ST elevation myocardial infarction (NSTEMI), and multivessel disease remains debated (MVD). The aim of our study was to determine the current long-term prognostic benefit of complete revascularization in this population. A retrospective cohort study of 1722 consecutive elderly NSTEMI patients was performed. Among the study participants 30.4% (n = 524) were completed revascularizated and in 69.6% (n = 1198) culprit vessel only revascularization was performed. A propensity score analysis was performed and we divided the study population into two groups: complete revascularization (n = 500) and culprit vessel only revascularization (n = 500). The median follow-up was 45.7 months, the all cause mortality (44.5% vs 30.5%, p < 0.001) (HR 0.74 (0.57–0.97); p = 0.035) and cardiovascular mortality (32.6% vs 17.4%, p < 0.001) (HR = 0.67 (0.47–0.94); p = 0.021) were significantly lower in patients with complete revascularization. In our study, we observed a long-term benefit of complete revascularization in elderly NSTEMI and MVD patients. Elderly patients should also be managed according to current guidelines to improve their long-term prognosis. |
| Databáze: | OpenAIRE |
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