Hepatic resection with cryotherapy to involved or inadequate resection margin (edge freeze) for metastases from colorectal cancer
| Autor: | Dwerryhouse Sj, David L. Morris, J. L. Mccall, Joachim K. Seifert, W. B. Ross, J. Iqbal |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer medicine.medical_treatment Rectum Cryotherapy Cryosurgery Metastasis Carcinoma Medicine Hepatectomy Humans Aged Aged 80 and over business.industry Liver Neoplasms Length of Stay Middle Aged medicine.disease Surgery medicine.anatomical_structure Treatment Outcome Resection margin Female Neoplasm Recurrence Local business Colorectal Neoplasms Follow-Up Studies |
| Zdroj: | The British journal of surgery. 85(2) |
| ISSN: | 0007-1323 |
| Popis: | Background In patients undergoing liver resection for colorectal liver metastases, a resection edge either involved by tumour or with the tumour extending to within 1 cm is associated with a high risk of liver recurrence and survival is reduced markedly. Methods Twenty-six patients underwent cryotherapy of the resection edge following liver resection for metastases from colorectal carcinoma with an involved or inadequate (less than 1 cm) resection margin. Results At a median follow-up of 23 (range 1–47) months four patients were alive and disease free, and 21 had developed recurrence, of whom 13 had died. One patient died following surgery. Sixteen patients developed recurrences involving the liver, only five of which were at the resection margin. Conclusion Cryotherapy to involved or inadequate resection margins improves local disease control considerably. The use of resection edge cryotherapy might allow a greater proportion of patients with liver metastases to be usefully treated and help to avoid high-risk resections. |
| Databáze: | OpenAIRE |
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