Invasive forms of Toxoplasma gondii, Leishmania amazonensis and Trypanosoma cruzi have a positive charge at their contact site with host cells

Autor: Mayumi Akaki, Masamichi Aikawa, Kouichi Nagakura, Eiji Nagayasu, Yamaji Nakano, Satoru Kawai
Rok vydání: 2001
Předmět:
Zdroj: Parasitology Research. 87:193-197
ISSN: 0932-0113
DOI: 10.1007/pl00008574
Popis: We examined the surface charges of invasive forms of Toxoplasma gondii, Leishmania amazonensis, and Trypanosoma cruzi by atomic force microscopy and surface potential spectroscopy. We found that the specific part of the protozoan which makes initial contact with the host cell is positively charged. This indicates that the positive charge at the site of contact facilitates binding of the invasive protozoan to negatively charged host cells.
Databáze: OpenAIRE