Maripa hantavirus in French Guiana: phylogenetic position and predicted spatial distribution of rodent hosts
| Autor: | Anne Lavergne, Amandine Guidez, François Catzeflis, Olivier Brunaux, Sébastien Barrioz, Luc Clément, Vincent Lacoste, Séverine Matheus, Stéphane Guitet, Damien Donato, Benoit de Thoisy, Jean-François Cornu |
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| Rok vydání: | 2014 |
| Předmět: |
Disease reservoir
Orthohantavirus DNA Complementary 030231 tropical medicine Zygodontomys brevicauda Molecular Sequence Data Zoology Rodentia Hantavirus Pulmonary Syndrome Antibodies Viral Kidney Rodent Diseases 03 medical and health sciences 0302 clinical medicine Phylogenetics Virology Animals Humans Lung Phylogeny 030304 developmental biology Hantavirus Demography Disease Reservoirs 0303 health sciences Hantavirus pulmonary syndrome biology Phylogenetic tree Base Sequence Geography Ecology Sequence Analysis DNA Articles biology.organism_classification French Guiana Infectious Diseases Oligoryzomys fulvescens RNA Viral Parasitology Bunyaviridae |
| Zdroj: | The American journal of tropical medicine and hygiene. 90(6) |
| ISSN: | 1476-1645 |
| Popis: | A molecular screening of wild-caught rodents was conducted in French Guiana, South America to identify hosts of the hantavirus Maripa described in 2008 in a hantavirus pulmonary syndrome (HPS) case. Over a 9-year period, 418 echimyids and murids were captured. Viral RNA was detected in two sigmodontine rodents, Oligoryzomys fulvescens and Zygodontomys brevicauda, trapped close to the house of a second HPS case that occurred in 2009 and an O. fulvescens close to the fourth HPS case identified in 2013. Sequences from the rodents had 96% and 97% nucleotide identity (fragment of S and M segments, respectively) with the sequence of the first human HPS case. Phylogenetic reconstruc-tions based on the complete sequence of the S segment show that Maripa virus is closely related to Rio Mamore hantavirus. Using environmental descriptors of trapping sites, including vegetation, landscape units, rain, and human disturbance, a maximal entropy-based species distribution model allowed for identification of areas of higher predicted occurrence of the two rodents, where emergence risks of Maripa virus are expected to be higher. Hantaviruses (Bunyaviridae) are distributed worldwide. |
| Databáze: | OpenAIRE |
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