Action-Outcome Knowledge Dissociates From Behavior in Obsessive-Compulsive Disorder Following Contingency Degradation
| Autor: | Rudolf N. Cardinal, Annemieke M. Apergis-Schoute, Naomi A. Fineberg, Trevor W. Robbins, Akeem Sule, Matilde M. Vaghi |
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| Přispěvatelé: | Cardinal, Rudolf [0000-0002-8751-5167], Robbins, Trevor [0000-0003-0642-5977], Apollo - University of Cambridge Repository |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Obsessive-Compulsive Disorder Frontostriatal Goal-directed Dysfunctional family Outcome (game theory) behavioral disciplines and activities 050105 experimental psychology Article 03 medical and health sciences Habits Judgment 0302 clinical medicine Obsessive compulsive Learning Humans 0501 psychology and cognitive sciences Action-outcome 05 social sciences Action control Middle Aged Causality humanities 3. Good health Action (philosophy) Habit Female Psychology Contingency Goals 030217 neurology & neurosurgery Psychomotor Performance Clinical psychology |
| Zdroj: | Biological Psychiatry. Cognitive Neuroscience and Neuroimaging |
| ISSN: | 2451-9030 2451-9022 |
| Popis: | BACKGROUND: In obsessive-compulsive disorder (OCD), actions persist despite being inappropriate to the situation and without relationship to the overall goal. Dysfunctional beliefs have traditionally been postulated to underlie this condition. More recently, OCD has been characterized in terms of an imbalance between the goal-directed and the habit systems. To test these competing hypotheses, we used a novel experimental task designed to test subjective action-outcome knowledge of the effectiveness of actions (i.e., instrumental contingency), together with the balance between goal-directed and habitual responding. METHODS: Twenty-seven patients with OCD and 27 healthy control subjects were tested on a novel task involving the degradation of an action-outcome contingency. Sensitivity to instrumental contingency and the extent to which explicitly reported action-outcome knowledge guided behavior were probed by measuring response rate and subjectively reported judgments. RESULTS: Patients with OCD responded more than healthy control subjects in situations in which an action was less causally related to obtaining an outcome. However, patients showed intact explicit action-outcome knowledge, as assessed by self-report. In patients, the relationship between causality judgment and responding was altered; therefore, their actions were dissociated from explicit action-outcome knowledge. CONCLUSIONS: These findings indicate reduced sensitivity to instrumental contingency in OCD, reinforcing the notion of a deficient goal-directed system in this disorder. By showing a dissociation between subjectively reported action-outcome knowledge and behavior, the data provide experimental evidence for the ego-dystonic nature of OCD. |
| Databáze: | OpenAIRE |
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