Usefulness of a 16S rDNA real-time PCR to monitor neonatal sepsis and to assist in medical decision to discontinue antibiotics

Autor: Maria Isabel Valdomir Nadaf, Patricia Palmeira, Thelma Suely Okay, Jonatas Cristian Rodrigues, Inês Stranieri, Lidia Yamamoto, Kelly Aparecida Kanunfre
Rok vydání: 2015
Předmět:
DNA
Bacterial
0301 basic medicine
medicine.medical_specialty
neonatal sepsis
medicine.drug_class
Decision Making
030106 microbiology
Antibiotics
Short Report
Pilot Projects
Real-Time Polymerase Chain Reaction
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
RNA
Ribosomal
16S
Report
16S rDNA
030225 pediatrics
Internal medicine
medicine
Humans
Intensive care medicine
RNA RIBOSOMAL 16S
Neonatal sepsis
business.industry
Infant
Newborn
Obstetrics and Gynecology
Prognosis
medicine.disease
Infant newborn
Predictive value
Bacterial Load
Anti-Bacterial Agents
real time PCR
Real-time polymerase chain reaction
Withholding Treatment
Predictive value of tests
quantitative PCR
Pediatrics
Perinatology and Child Health
Drug Monitoring
business
REAÇÃO EM CADEIA POR POLIMERASE
Zdroj: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The Journal of Maternal-Fetal & Neonatal Medicine
ISSN: 1476-4954
1476-7058
Popis: Objective: To monitor the bacterial load in newborns with proven infections on the day of admission, 48 h and 7 days after treatment. Methods: Real-time PCR (qPCR) targeting the 16S rDNA. Results: The study recruited 17 newborns and the bacterial load was in general low (
Databáze: OpenAIRE
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