Autor: |
Gillian C. Barnett, Catherine M West, Alison M. Dunning, Neil G. Burnet, Paul D.P. Pharoah, Rebecca Elliott, Charlotte E. Coles |
Jazyk: |
angličtina |
Rok vydání: |
2009 |
Předmět: |
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Popis: |
A key challenge in radiotherapy is to maximize radiation doses to cancer cells while minimizing damage to surrounding healthy tissue. As severe toxicity in a minority of patients limits the doses that can be safely given to the majority, there is interest in developing a test to measure an individual's radiosensitivity before treatment. Variation in sensitivity to radiation is an inherited genetic trait and recent progress in genotyping raises the possibility of genome-wide studies to characterize genetic profiles that predict patient response to radiotherapy. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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