Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists
Autor: | S. S. Tucker, J. F. Devan, R. M. Muccitelli, M A Wasserman, T. Kirchner, Carl D. Perchonock, Erhard Kf, L. M. Vickery, John G. Gleason, McCarthy Me |
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Rok vydání: | 1985 |
Předmět: |
chemistry.chemical_classification
Receptors Leukotriene Leukotriene Leukotriene Antagonists Chemical Phenomena Dose-Response Relationship Drug Stereochemistry Carboxylic acid Airway Resistance Guinea Pigs Receptors Prostaglandin Biological activity Trachea Chemistry chemistry Chromones Drug Discovery Molecular Medicine Animals Dicarboxylic Acids SRS-A Lung Compliance Muscle Contraction |
Zdroj: | Journal of medicinal chemistry. 28(9) |
ISSN: | 0022-2623 |
Databáze: | OpenAIRE |
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