An analysis of clinical predictive values for radiographic pneumonia in children
| Autor: | Rees, CA, Basnet, S, Gentile, A, Gessner, BD, Kartasasmita, CB, Lucero, M, Martinez, L, O'Grady, K-AF, Ruvinsky, RO, Turner, C, Campbell, H, Nair, H, Falconer, J, Williams, LJ, Horne, M, Strand, T, Nisar, YB, Qazi, SA, Neuman, MI, group, World Health Organization PREPARE study |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Pleural effusion Radiography Tachypnea Sensitivity and Specificity Hypoxemia 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Clinical endpoint pneumonia Humans 030212 general & internal medicine Child Original Research Lung medicine.diagnostic_test business.industry Health Policy Public Health Environmental and Occupational Health medicine.disease respiratory tract diseases Pneumonia medicine.anatomical_structure child health medicine.symptom business Chest radiograph |
| Zdroj: | Rees, C, Sudha, B, Gentile, A, Gessner, B, Kartasasmita, C, Lucero, M, Martinez, L, O'Grady, K-A, Ruvinsky, R, Turner, C, Campbell, H, Nair, H, Falconer, J, Williams, L J, Horne, M, Strand, T, Nisar, Y & Qazi, S 2020, ' An analysis of clinical predictive values for radiographic pneumonia in children ', BMJ Global Health, vol. 5, no. 8 . https://doi.org/10.1136/bmjgh-2020-002708 BMJ Global Health e002708 |
| Popis: | Introduction: Healthcare providers in resource-limited settings rely on the presence of tachypnoea and chest indrawing to establish a diagnosis of pneumonia in children. We aimed to determine the test characteristics of commonly assessed signs and symptoms for the radiographic diagnosis of pneumonia in children 0-59 months of age. Methods: We conducted an analysis using patient-level pooled data from 41 shared datasets of paediatric pneumonia. We included hospital-based studies in which >80% of children had chest radiography performed. Primary endpoint pneumonia (presence of dense opacity occupying a portion or entire lobe of the lung or presence of pleural effusion on chest radiograph) was used as the reference criterion radiographic standard. We assessed the sensitivity, specificity, and likelihood ratios for clinical findings, and combinations of findings, for the diagnosis of primary endpoint pneumonia among children 0-59 months of age. Results: Ten studies met inclusion criteria comprising 15 029 children; 24.9% (n=3743) had radiographic pneumonia. The presence of age-based tachypnoea demonstrated a sensitivity of 0.92 and a specificity of 0.22 while lower chest indrawing revealed a sensitivity of 0.74 and specificity of 0.15 for the diagnosis of radiographic pneumonia. The sensitivity and specificity for oxygen saturation |
| Databáze: | OpenAIRE |
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