Congenital hypothyroidism in different cities of the Isfahan province: A descriptive retrospective study
| Autor: | Roya Kelishadi, Marzie Dalvi, Zeinab Hemati, Masoud Zandieh, Serajoddin Arefnia, Marjan Mansourian, Mahshid Ahmadian, Mahin Hashemipour, Silva Hovsepian |
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| Rok vydání: | 2019 |
| Předmět: |
lcsh:LC8-6691
medicine.medical_specialty High prevalence lcsh:Special aspects of education medicine.diagnostic_test business.industry lcsh:Public aspects of medicine permanent congenital hypothyroidism Prevalence Medicine (miscellaneous) lcsh:RA1-1270 Retrospective cohort study medicine.disease Thyroid function tests Education Congenital hypothyroidism Epidemiology medicine Etiology Original Article business Live birth transient congenital hypothyroidism Demography |
| Zdroj: | Journal of Education and Health Promotion Journal of Education and Health Promotion, Vol 8, Iss 1, Pp 137-137 (2019) |
| ISSN: | 2277-9531 |
| Popis: | BACKGROUND: Considering the high prevalence rate of congenital hypothyroidism CH in Iran, an epidemiological study in each region would be helpful in understanding the etiology of the disorder and providing preventative strategies in this field. This study aims to determine the prevalence of CH in different cities of the Isfahan province. MATERIALS AND METHODS: This descriptive and retrospective study was conducted among 918 primarily diagnosed CH neonates, who have been identified through the neonatal screening program from 2009 to 2015. At the age of ≥3 years, treatment was discontinued for 4 weeks, and T4 and thyroid-stimulating hormone were measured. Permanent (PCH) or transient (TCH) was determined from the results of the thyroid function tests. RESULTS: From 389,101 screened neonates, 918 were diagnosed with primary CH. The overall prevalence rate of CH was 2.36 in 1000 live birth (ranged 1.58–7.22 in 1000 live birth in different cities). The highest prevalence rate of CH was reported in Ardestan, Khansar, Golpaygan, and Nain cities with prevalence rate of 4.86–7.22 in 1000 live birth and lowest prevalence occurring in Fereydan, Shahreza, Isfahan, and Mobarakeh cities with prevalence rate of 1.58–1.89 in 1000 live birth. In 392 cases which reached to 3 years of age, the rate of TCH was 47.45%. In Chadegan, Natanz, Fereydunshahr, Shahinshahr, Najafabad, Dehaghan, Borkhar, and Mobarakeh, the prevalence of PCH was |
| Databáze: | OpenAIRE |
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