Familial Transmissability of Early Age at Initial Diagnosis in Coronary Heart Disease (CHD): Males Only, and Mediated by Psychosocial/Emotional Distress?
| Autor: | Adam B. Greenbaum, Arif Hakim, Johan Denollet, Jeanine Chapp, John R. Schairer, J. Jane Cao, A. J. Farha, Michael P. Hudson, S. J. Keteyian, Vivian Clark, Mark W. Ketterer |
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| Přispěvatelé: | Medical and Clinical Psychology |
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Time Factors media_common.quotation_subject Coronary Disease ComputingMilieux_LEGALASPECTSOFCOMPUTING Disease Anger Anxiety Genetic determinism Developmental psychology Sex Factors Surveys and Questionnaires Humans Age of Onset Family history General Psychology Depression (differential diagnoses) Aged media_common Chi-Square Distribution Depression Middle Aged Psychiatry and Mental health Spouse Female Age of onset Psychology Psychosocial Stress Psychological Demography |
| Zdroj: | Journal of Behavioral Medicine, 27(1), 1-10. KLUWER ACADEMIC/PLENUM PUBL |
| ISSN: | 0160-7715 |
| DOI: | 10.1023/b:jobm.0000013640.69802.fa |
| Popis: | In equal sized samples, a strong association between a positive Family History of Early Coronary Heart Disease (FamHx) and early Age at Initial Diagnosis (AAID) was found only for males, and thus all further analyses were restricted to males. All three scales of the self-report version of the Ketterer Stress Symptom Frequency Checklist--Revised (KSSFCR)--"AIAI" (or aggravation, irritation, anger, and impatience), Depression, and Anxiety--were associated with both a positive FamHx and early AAID. A series of regression models was used to demonstrate that the KSSFCR scales may plausibly account for 22-32% of the variance in the relationship between a positive FamHx and early AAID. Because of previously documented denial in males, the analyses were repeated in a subgroup of males for whom Spouse/Friend KSSFCRs were obtained. Spouse/Friend-reported AIAI was related to both early FamHx and early AAID, and could account for 68% of the common variance. |
| Databáze: | OpenAIRE |
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