Clinical Analyses of Sighted Patients with Non-24-Hour Sleep-Wake Syndrome: A Study of 57 Consecutively Diagnosed Cases
| Autor: | Kayo Shibui, Masako Okawa, Tatsuro Hayakawa, Yuichi Kamei, Jujiro Urata, Kiyohisa Takahashi, Takashi Asada, Hirokuni Tagaya, Makoto Uchiyama |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Obsessive-Compulsive Disorder medicine.medical_specialty Pediatrics Neurology Signs and symptoms Severity of Illness Index Cohort Studies Sleep Disorders Circadian Rhythm Intellectual Disability Physiology (medical) Interview Psychological Severity of illness Prevalence medicine Humans Referral and Consultation Depression (differential diagnoses) Depressive Disorder Major business.industry Anxiety Disorders Circadian Rhythm Cohort Schizophrenia Physical therapy Female Hour sleep Neurology (clinical) Psychiatric interview business Cohort study |
| Zdroj: | Sleep. 28:945-952 |
| ISSN: | 1550-9109 0161-8105 |
| Popis: | Study objectives The objective of this study was to clarify the clinical features of sighted patients with non-24-hour sleep-wake syndrome. Design Clinical analyses of consecutive patients suffering from non-24-hour sleep-wake syndrome. Setting The sleep disorders clinic at Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan. Patients Fifty-seven patients who were diagnosed consecutively as having non-24-hour sleep-wake syndrome between 1991 and 2001 were included in the study. Measurements and results The clinical features and sleep characteristics of the patients were analyzed. A semistructured psychiatric interview that included the criteria for Axis I or II disorders of Diagnostic and Statistical Manual of Mental Disorders, Third Edition-Revised was conducted, and relationships between psychiatric problems and non-24-hour sleep-wake syndrome were analyzed. The patient cohort included 41 (72%) men and 16 (28%) women. The onset of non-24-hour sleep-wake syndrome had occurred during the teenage years in 63% of the cohort, and the mean ( +/-SD) period of the sleep-wake cycle was 24.9 +/- 0.4 hours (range 24.4-26.5 hours). The mean sleep length of the patients was 9.3 +/- 1.3 hours, and 44% of them had a sleep length of between 9 and 10 hours. Psychiatric disorders had preceded the onset of non-24-hour sleep-wake syndrome in 16 patients (28%); of the remaining 41 patients, 14 (34%) developed major depression after the onset of non-24-hour sleep-wake syndrome. Conclusions These results represent the first detailed clinical review of a relatively large number of sighted patients with non-24-hour sleep-wake syndrome. |
| Databáze: | OpenAIRE |
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