Utility of a Commercial PCR Assay and a Clinical Prediction Rule for Detection of Toxigenic Clostridium difficile in Asymptomatic Carriers

Autor:	Curtis J. Donskey, Susan P. Sambol, Venkata C. K. Sunkesula, Matthew H. Samore, Susan M. Pacheco, Laurica A. Petrella, Jeanmarie Mayer, Carolyn V. Gould, Nimalie D. Stone, Dale N. Gerding, L. Clifford McDonald, Deborah Terry, Annette L. Jencson
Rok vydání:	2014
Předmět:	Adult Aged 80 and over Male Microbiology (medical) Clostridioides difficile business.industry Bacterial Toxins Pcr assay Rectum Bacteriology Clinical prediction rule Middle Aged Clostridium difficile Polymerase Chain Reaction Virology Decision Support Techniques Microbiology Carrier State Clostridium Infections Humans Medicine Female business Asymptomatic carrier Aged
Zdroj:	Journal of Clinical Microbiology. 52:315-318
ISSN:	1098-660X 0095-1137
Popis:	A commercial PCR assay of perirectal swab specimens detected 17 (68%) of 25 asymptomatic carriers of toxigenic Clostridium difficile , including 93% with skin and/or environmental contamination. A clinical prediction rule, followed by PCR screening, could be used to identify carriers at high risk of C. difficile shedding.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8751fb25c19c52197a2c435d5b55c5d https://doi.org/10.1128/jcm.01852-13 Zobrazit plný text záznamu