Hepatosplenic Cat‐Scratch Disease in Children: Selected Clinical Features and Treatment
| Autor: | Sheldon L. Kaplan, E. S. Arisoy, M. L. Wagner, Armando G. Correa |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Abdominal pain medicine.drug_class Antibiotics Internal medicine medicine Animals Humans Child Splenic Diseases Antibacterial agent business.industry Liver Diseases Cat-Scratch Disease Cat-scratch disease medicine.disease Trimethoprim Anti-Bacterial Agents Surgery Infectious Diseases El Niño Child Preschool Cats Rifampin Splenic disease medicine.symptom business Rifampicin medicine.drug |
| Zdroj: | Clinical Infectious Diseases. 28:778-784 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1086/515197 |
| Popis: | We reviewed 19 cases of hepatosplenic cat-scratch disease at Texas Children's Hospital (Houston). The range of the patients' ages was 2 years 4 months to 11 years 8 months. The chief complaint was fever for all patients. The duration of fever before diagnosis was 7 to 56 days (mean, 22 days). Abdominal pain was present in 13 patients (68%). Thirteen children were treated with rifampin alone, and three received rifampin therapy plus gentamicin or trimethoprim-sulfamethoxazole. Once rifampin therapy was initiated alone or in combination, improvement was noted within 1 to 5 days (mean, 2.6 days) for patients who had had prolonged fever the duration of which before rifampin therapy averaged 3 weeks. The most common dosage and duration for our patients were 20 mg/[kg x d] every 12 hours and 14 days, respectively. Rifampin should be considered in the initial antimicrobial treatment of hepatosplenic cat-scratch disease. |
| Databáze: | OpenAIRE |
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