Imaging of Acute Invasive Fungal Rhinosinusitis in a Patient with Gorlin Syndrome and Acute Lymphocytic Leukemia
| Autor: | Jerome W. Thompson, S. T. Donovan, John T. Sandlund, J. H. Harreld, E. E. Adderson, E. K. Pivnick |
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| Rok vydání: | 2013 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test business.industry Case Report Nevoid basal-cell carcinoma syndrome Computed tomography General Medicine lcsh:Otorhinolaryngology medicine.disease lcsh:RF1-547 3. Good health 03 medical and health sciences High morbidity Pediatric patient 0302 clinical medicine 030220 oncology & carcinogenesis Acute lymphocytic leukemia medicine In patient business Clinical scenario 030217 neurology & neurosurgery |
| Zdroj: | Case Reports in Otolaryngology Case Reports in Otolaryngology, Vol 2013 (2013) |
| ISSN: | 2090-6773 2090-6765 |
| DOI: | 10.1155/2013/272314 |
| Popis: | Gorlin Syndrome (GS), also known as nevoid basal cell carcinoma syndrome, is a rare autosomal dominant condition characterized by developmental abnormalities and predisposition to certain neoplasms. Acute invasive fungal rhinosinusitis (AIFRS) is an uncommon clinical entity characterized by high morbidity and mortality. In immunocompromised patients, computed tomography plays a critical role in screening for suspected AIFRS. However, due to the association between exposure to ionizing radiation and subsequent development of malignancies in patients with GS, patients with GS and suspected AIFRS present a unique and challenging clinical scenario. We present a case of a pediatric patient with GS and acute lymphocytic leukemia (ALL) diagnosed with AIFRS; to the best of our knowledge, it is the only case described in the literature. |
| Databáze: | OpenAIRE |
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