Post-herpetic neuralgia and topical capsaicin
Autor: | Verna R. Watt, C.Peter N. Watson, Ramon J. Evans |
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Rok vydání: | 1988 |
Předmět: |
Adult
Male medicine.medical_specialty Palliative care Patient Dropouts medicine.medical_treatment Administration Topical Pain relief Sensation Herpes Zoster law.invention Randomized controlled trial law Medicine Humans Paresthesia Aged Chemotherapy Topical capsaicin business.industry Palliative Care Follow up studies Middle Aged medicine.disease Surgery Anesthesiology and Pain Medicine Neurology Post-herpetic neuralgia Anesthesia Neuralgia Female Neurology (clinical) Capsaicin business Follow-Up Studies |
Zdroj: | Pain. 33(3) |
ISSN: | 0304-3959 |
Popis: | Topical 0.025% capsaicin was used to treat 33 patients with post-herpetic neuralgia (PHN). Thirty-nine percent of those entering the trial achieved at least a good result and 55% were improved or better. Fifty-six percent of the 23 patients completing the study had good or excellent pain relief after 4 weeks. Seventy-eight percent of the 23 noted at least some improvement in pain. Post-capsaicin burning was a common, untoward effect in most patients and in about one-third was so unbearable that the trial was terminated prematurely. This treatment appears to be a useful modality in PHN, particularly in the elderly in whom oral medications are often poorly tolerated; however, it does require supervision. A double-blind, controlled trial is now necessary. |
Databáze: | OpenAIRE |
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