Post-herpetic neuralgia and topical capsaicin

Autor: Verna R. Watt, C.Peter N. Watson, Ramon J. Evans
Rok vydání: 1988
Předmět:
Zdroj: Pain. 33(3)
ISSN: 0304-3959
Popis: Topical 0.025% capsaicin was used to treat 33 patients with post-herpetic neuralgia (PHN). Thirty-nine percent of those entering the trial achieved at least a good result and 55% were improved or better. Fifty-six percent of the 23 patients completing the study had good or excellent pain relief after 4 weeks. Seventy-eight percent of the 23 noted at least some improvement in pain. Post-capsaicin burning was a common, untoward effect in most patients and in about one-third was so unbearable that the trial was terminated prematurely. This treatment appears to be a useful modality in PHN, particularly in the elderly in whom oral medications are often poorly tolerated; however, it does require supervision. A double-blind, controlled trial is now necessary.
Databáze: OpenAIRE