| Autor: |
A. V. Babakhanyan, G. A. Panosyan, V. S. Voskanyan, S. T. Kocharian, V. E. Karapetian, S. A. Hovakimyan |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Chemistry of Heterocyclic Compounds. 40:1047-1051 |
| ISSN: |
0009-3122 |
| DOI: |
10.1023/b:cohc.0000046696.37815.62 |
| Popis: |
The reaction of methyl esters of 3-methyl-2-oxo- and 2-oxo-3-phenyl-3-pentenoic acids with hydrazine hydrate and phenylhydrazine was used to synthesize new pyridazinone derivatives. These products are formed through intermediate hydrazides with subsequent cyclization. 4-Hydroxy-3-oxotetrahydropyridazines are mainly formed using equimolar amounts of the starting reagents, while the corresponding hydrazones of 3,4-dioxohexahydropyridazines are formed in the case of a two-fold excess of hydrazine hydrate or phenylhydrazine. Evidence was obtained indicating the existence of a keto–enol tautomerism for 4-hydroxy-3-oxopyridazines. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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