Ultrafast Detection of Sulfur Dioxide Derivatives by a Distinctive 'Dual-Positive-Ion' Platform that Features a Doubly Activated but Irreversible Michael Addition Site
| Autor: | Yong Yuan, Congde Huo, Xiazhen Bao, Xuehui Cao, Bo Zhou |
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| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
complex mixtures 01 natural sciences Fluorescence Ion chemistry.chemical_compound Animals Humans Sulfur Dioxide Molecule Zebrafish Sulfur dioxide Fluorescent Dyes Detection limit Aqueous solution Chemistry 010401 analytical chemistry General Chemistry Combinatorial chemistry respiratory tract diseases 0104 chemical sciences Reagent Michael reaction General Agricultural and Biological Sciences HeLa Cells 010606 plant biology & botany |
| Zdroj: | Journal of Agricultural and Food Chemistry. 69:4903-4910 |
| ISSN: | 1520-5118 0021-8561 |
| Popis: | Sulfur dioxide (SO2) is a gaseous signaling molecule and widely used as a preservative for foods, but its excessive intake is closely related to a series of diseases. Therefore, the development of a potent fluorescence probe for the detection of SO2 in foods and biological systems is of great significance. Herein, we report for the first time a "dual-positive-ion" platform-based fluorescence probe CMQ, designed by a doubly activated but irreversible strategy, which results in its ultrafast response to SO2 within 5 s in pure aqueous solution together with a low detection limit as 15.6 nM. In addition, the probe was successfully applied for imaging of SO2 in mitochondria of living cells and zebrafish and prepared as a reagent kit for convenient and instantaneous quantification of HSO3- in real food samples. |
| Databáze: | OpenAIRE |
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