Interference of peptides and specific antibodies with the function of the Actinobacillus pleuropneumoniae transferrin-binding protein
| Autor: | Burkart Franz, Katrin Strutzberg, Gerald-F. Gerlach |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Immunology
Molecular Sequence Data Peptide Plasma protein binding Microbiology law.invention Bacterial Proteins law Amino Acid Sequence Peptide sequence Actinobacillus pleuropneumoniae chemistry.chemical_classification biology Binding protein Transferrin biology.organism_classification Molecular biology Antibodies Bacterial Infectious Diseases Biochemistry chemistry Recombinant DNA biology.protein Parasitology Antibody Peptides Protein Binding Research Article |
| Zdroj: | Infection and immunity. 65(12) |
| ISSN: | 0019-9567 |
| Popis: | Multiple-antigenic peptides (MAPs) containing transferrin-binding domains of the Actinobacillus pleuropneumoniae serotype 7-derived transferrin-binding protein (TfbA) (K. Strutzberg, L. von Olleschik, B. Franz, C. Pyne, M. A. Schmidt, and G.-F. Gerlach, Infect. Immun. 63:3846-3850, 1995) were constructed. It was found that the MAPs inhibited transferrin binding of the recombinant TfbA protein, whereas antibodies directed against transferrin-binding domains failed to do so. |
| Databáze: | OpenAIRE |
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