Effect of shampoo, conditioner and permanent waving on the molecular structure of human hair
| Autor: | Asfia Soomro, Yuchen Zhang, Maikel C. Rheinstädter, Fei Chi Yang, Richard J. Alsop |
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| Rok vydání: | 2015 |
| Předmět: |
Biophysics
lcsh:Medicine macromolecular substances General Biochemistry Genetics and Molecular Biology Cell membrane Hair care products Keratin medicine Molecule Intermediate filament Conditioner Medulla Shampoo Cuticle (hair) chemistry.chemical_classification integumentary system Chemistry General Neuroscience lcsh:R Biomaterial General Medicine Anatomy X-ray diffraction Human hair medicine.anatomical_structure sense organs General Agricultural and Biological Sciences Molecular structure Permanent waving |
| Zdroj: | PeerJ PeerJ, Vol 3, p e1296 (2015) |
| ISSN: | 2167-8359 |
| DOI: | 10.7717/peerj.1296 |
| Popis: | The hair is a filamentous biomaterial consisting of thecuticle, thecortexand themedulla, all held together by the cell membrane complex. Thecortexmostly consists of helical keratin proteins that spiral together to form coiled-coil dimers, intermediate filaments, micro-fibrils and macro-fibrils. We used X-ray diffraction to study hair structure on the molecular level, at length scales between ∼3–90 Å, in hopes of developing a diagnostic method for diseases affecting hair structure allowing for fast and noninvasive screening. However, such an approach can only be successful if common hair treatments do not affect molecular hair structure. We found that a single use of shampoo and conditioner has no effect on packing of keratin molecules, structure of the intermediate filaments or internal lipid composition of the membrane complex. Permanent waving treatments are known to break and reform disulfide linkages in the hair. Single application of a perming product was found to deeply penetrate the hair and reduce the number of keratin coiled-coils and change the structure of the intermediate filaments. Signals related to the coiled-coil structure of theα-keratin molecules at 5 and 9.5 Å were found to be decreased while a signal associated with the organization of the intermediate filaments at 47 Å was significantly elevated in permed hair. Both these observations are related to breaking of the bonds between two coiled-coil keratin dimers. |
| Databáze: | OpenAIRE |
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