Scrub Typhus and Abnormal Electrocardiography
Autor: | Seok Won Kim, Dong-Hyun Choi, Choon-Mee Kim, Dong-Min Kim, Seo-Won Choi, Na Ra Yun, Young-Jae Ki |
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Rok vydání: | 2019 |
Předmět: |
Male
medicine.medical_specialty Orientia tsutsugamushi 030231 tropical medicine Myocardial Ischemia Scrub typhus Severity of Illness Index QT interval Electrocardiography 03 medical and health sciences 0302 clinical medicine Virology Internal medicine Severity of illness medicine Humans Aged Retrospective Studies integumentary system medicine.diagnostic_test biology business.industry Case-control study Arrhythmias Cardiac Retrospective cohort study Articles Middle Aged bacterial infections and mycoses medicine.disease University hospital biology.organism_classification Long QT Syndrome Infectious Diseases Scrub Typhus Case-Control Studies Female Parasitology business Blood Chemical Analysis |
Zdroj: | The American Journal of Tropical Medicine and Hygiene. 100:399-404 |
ISSN: | 1476-1645 0002-9637 |
DOI: | 10.4269/ajtmh.17-0565 |
Popis: | This study compared the frequency of abnormal electrocardiogram (ECG) types between scrub typhus patient group and age- and gender-matched health checkup group and their associations with disease severity in scrub typhus patient. Demographic characteristics and ECG and laboratory findings of patients with scrub typhus admitted to Chosun University Hospital, and normal subjects visiting the hospital for health checkup from January 2008 to December 2012 were retrospectively studied. Electrocardiogram abnormalities at admission were observed in 72 of 165 (43.6%) scrub typhus confirmed patients. The following ECG abnormalities were observed: arrhythmic group (31 cases, 18.8%), ischemic change group (25 cases, 15.1%), prolonged QT group (32 cases, 19.4%).Compared with the age and gender-matched health checkup group, ECG abnormalities were more commonly observed in scrub typhus patient group (13.9% versus 43.6%, P < 0.001). In addition, when compared with the normal ECG group, scrub typhus in the abnormal ECG group showed greater disease severity and this phenomenon was particularly prominent in the prolonged QT group. Based on our study prolonged QT observed in approximately 20% of patients with scrub typhus, clinicians should pay additional attention to drugs that affect QT interval. |
Databáze: | OpenAIRE |
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