Increased annual frequency of Hashimoto's thyroiditis between years 1988 and 2007 at a cytological unit of Sicily

Autor: Claudio Scisca, Calbo L, Massimo Rizzo, Salvatore Benvenga, Alessandro Sindoni, Raffaele Talamo Rossi, Francesco Trimarchi, Giuseppe Altavilla, Orsola Bonaffini, Antonio Rosano
Rok vydání: 2009
Předmět:
Zdroj: Annales d'endocrinologie. 71(6)
ISSN: 2213-3941
Popis: Like other auto-immune diseases, Hashimoto's thyroiditis (HT) results from the interaction of genetic with environmental factors. Only few studies have evaluated the year-to-year change in frequency of HT over a wide period of time. The endocrine division of our Hospital has reported a great increase in the annual frequency of HT between 1975 and 2005, and a progressive decrease in both age at presentation and female to male (F/M) ratio starting in the mid-1990s. Between years 1988 and 2007, we have collected 8397 adequate examinations by fine needle aspiration cytology (FNAC) on 8397 persons referred for the evaluation of a solitary or dominant thyroid nodule (total FNAC and persons=8520) with a 14-fold increase in 2007 over 1988. In this 20-year period, cases of HT, De Quervain's thyroiditis (DQT) and Riedel's thyroiditis (RT) were 490, 36 and two, respectively. HT cases were one in 1988 but 90 in 2007, with a significant upward temporal trend (r=0.919, P
Databáze: OpenAIRE