Emerging methods in therapeutics using multifunctional nanoparticles
| Autor: | Nahal Habibi, Joerg Lahann, Daniel F Quevedo, Jason V. Gregory |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Life sciences
biology Clinical Trials as Topic Computer science Multifunctional nanoparticles Biomedical Engineering Cancer therapy Medicine (miscellaneous) Proteins Bioengineering Nanotechnology 02 engineering and technology Multifunctional Nanoparticles 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Nanomedicine ddc:570 Drug delivery Anisotropy Humans Nanoparticles Poor circulation 0210 nano-technology |
| Zdroj: | Wiley interdisciplinary reviews / Nanomedicine and Nanobiotechnology, 12 (4), Art. Nr.: e1625 |
| ISSN: | 1939-5116 1939-0041 |
| DOI: | 10.5445/ir/1000125327 |
| Popis: | Clinical translation of nanoparticle-based drug delivery systems is hindered by an array of challenges including poor circulation time and limited targeting. Novel approaches including designing multifunctional particles, cell-mediated delivery systems, and fabrications of protein-based nanoparticles have gained attention to provide new perspectives to current drug delivery obstacles in the interdisciplinary field of nanomedicine. Collectively, these nanoparticle devices are currently being investigated for applications spanning from drug delivery and cancer therapy to medical imaging and immunotherapy. Here, we review the current state of the field, highlight opportunities, identify challenges, and present the future directions of the next generation of multifunctional nanoparticle drug delivery platforms. This article is categorized under: Biology-Inspired Nanomaterials > Protein and Virus-Based Structures Nanotechnology Approaches to Biology > Nanoscale Systems in Biology. |
| Databáze: | OpenAIRE |
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