Chemical and Electrochemical Oxidation of C8-Arylamine Adducts of 2‘-Deoxyguanosine

Autor:	Carmelo J. Rizzo, Madalina Ciobanu, James S. Stover, David E. Cliffel
Rok vydání:	2007
Předmět:	Chemistry Organic solvent Aryl Deoxyguanosine Oxidation reduction General Chemistry Photochemistry Electrochemistry Biochemistry Article Catalysis Adduct chemistry.chemical_compound Colloid and Surface Chemistry Aqueous buffer Polymer chemistry Amines Oxidation-Reduction Voltammetry
Zdroj:	Journal of the American Chemical Society. 129:2074-2081
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja066404u
Popis:	The electrochemical and chemical oxidation of a series of C8-arylamine adducts of 2'-deoxyguanosine has been examined. The oxidations were found to be reversible by cyclic and square-wave voltammetry in both aqueous buffer and aprotic organic solvent. The mechanism of the oxidation in protic media was either one- or two-electron, depending on the aryl group. The chemical oxidation resulted in guanidinohydantoin and spiroiminodihydantoin rearrangement products similar to those observed for 8-oxo-7,8-dihydro-2'-deoxyguanosine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83c324993d9b3234ba00c2302a541b5 https://doi.org/10.1021/ja066404u Zobrazit plný text záznamu