Hydrogen Peroxide Disinfecting Solution for Gas Permeable Contact Lenses: A Review of the Antimicrobial Efficacy, Compatibility, and Safety Performance of a One-Step Lens Care System
| Autor: | Huagang Chen, Sruthi Srinivasan, Cynthia McAnally, Manal M. Gabriel, Venkiteshwar Manoj, Renee Garofalo |
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| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
gas permeable contact lenses Disinfectant Antimicrobial efficacy Acanthamoeba species CLEAR CARE PLUS Clinical performance Review Sensory Systems law.invention AOSEPT PLUS with HydraGlyde lens care Lens (optics) Ophthalmology chemistry.chemical_compound chemistry law immune system diseases Compatibility (mechanics) Hydrogen peroxide skin and connective tissue diseases antimicrobial efficacy Biomedical engineering |
| Zdroj: | Clinical Optometry |
| ISSN: | 1179-2752 |
| Popis: | CLEAR CARE PLUS (CCP), also known as AOSEPT PLUS with HydraGlyde, is approved for use with gas permeable (GP) lenses, and the indication is supported by the scientific evidence that is reviewed in this article. Antimicrobial efficacy testing of CCP both as a stand-alone disinfectant and as part of a regimen shows that CCP exceeds the ISO 14729 criteria against bacteria, yeast, and mold. In real-world conditions, it is effective against clinically relevant bacterial strains isolated from adverse events and against the two forms, trophozoites and cysts, of resilient Acanthamoeba species. Compatibility tests of CCP with two types of GP lenses indicate that the physical and/or optical parameters of lenses are unaffected through 30 cycles of simulated use with CCP, and a clinical trial shows substantial equivalence of clinical performance with a commonly used GP multipurpose solution. These results indicate that CCP is well suited for cleaning and disinfection of GP contact lenses. |
| Databáze: | OpenAIRE |
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