A new haplotype of the beta-globin gene complex, Hbbw1, in Chinese wild mouse
| Autor: | Kazuo Moriwaki, Mei-Lei Jin, Tsuyoshi Kawashima, Nobumoto Miyashita, Xinquao He, Chenghuai Wang, Zhengan Wu |
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| Rok vydání: | 1991 |
| Předmět: |
Genetics
China Hemeprotein Haplotype Protein primary structure Animals Wild Mice Inbred Strains General Medicine Electrophoresis Cellulose Acetate Biology Molecular biology Globins Mice Gene Frequency Haplotypes Animals Electrophoresis Polyacrylamide Gel Globin Hemoglobin Gene Allele frequency Polyacrylamide gel electrophoresis |
| Zdroj: | Idengaku zasshi. 66(4) |
| ISSN: | 0021-504X |
| Popis: | A new pattern was observed in the electrophoretic survey of the hemoglobin beta chain (Hbb) in Chinese wild mice, Mus musculus. The electrophoretic mobility of the major component of the new Hbb was identical to that of Hbbs on cellulose acetate plate, although it was almost identical to that of Hbbd or Hbbp on acrylamide gel. This suggests that the major component of Chinese Hbb has a unique primary structure. A minor component of the new Hbb was completely different from that of the other three Hbb haplotypes well known. These results indicate that the Hbb-b1 and Hbb-b2 of the new Hbb haplotype, assigned Hbbw1, are unique genes in their molecular structure. So far, Hbbw1 has been observed in northwestern China. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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