Impact of Mediterranean Diet prior to Stroke on the Prognosis of Patients Undergoing Endovascular Treatment
| Autor: | Mar Castellanos, Herbert Tejada-Meza, Cristina Pérez, Nordictus investigators, Elena López-Cancio, Maria Castañón-Apilánez, Ana Pinedo, Lorena Benavente-Fernández, Jose Maria Jimenez, Joaquín Sánchez, Francisco Julian-Villaverde, Maite Martínez-Zabaleta, Emilio Rodríguez-Castro, Enrique Palacio, Gabriela Rodrigo-Stevens, Carmen García-Cabo, Juan F. Arenillas |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Prognostic variable Time Factors Mediterranean diet medicine.medical_treatment Wine Lower risk Diet Mediterranean Disability Evaluation Modified Rankin Scale Internal medicine Medicine Humans Prospective Studies Stroke Olive Oil Aged Thrombectomy Aged 80 and over business.industry Cerebral infarction Endovascular Procedures Thrombolysis Middle Aged medicine.disease Treatment Outcome Neurology Spain Patient Compliance Observational study Female Neurology (clinical) Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cerebrovascular diseases (Basel, Switzerland). 50(3) |
| ISSN: | 1421-9786 |
| Popis: | Introduction: Mediterranean diet (MeDiet) has been associated with lower risk of stroke. Additionally, animal models suggested that some components of MeDiet are associated with better outcomes after ischemic stroke (IS). We aimed to evaluate the association between global adherence to the MeDiet and the consumption of particular components of the MeDiet with stroke outcomes. Material and Methods: Multicenter observational study of consecutive IS patients treated with endovascular therapy. Inclusion criteria were large anterior circulation vessel occlusion and pre-stroke modified Rankin scale (mRS) Results: From January 1 to October 30, 2018, 239 patients were included (mean age 71 years, 48% women, median baseline NIHSS 16). Median MEDAS scale was 8 points (7–10). Patients with a higher adherence to MeDiet had significantly lower total and LDL-cholesterol levels. Total adherence score was not associated with stroke outcomes. In multivariate analyses, consumption of olive oil as the principal source of fat was independently associated with good functional outcome at 3 months, OR 3.2 (1.1–10.1) and daily consumption of wine was independently associated with complete recanalization, OR 2.0 (1.1–3.8). Conclusions: Our study suggests that some components of MeDiet, such as olive oil and wine consumption, are related to better prognosis after stroke. More studies are needed to confirm these findings. |
| Databáze: | OpenAIRE |
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