Unique characteristics of new complete blood count parameters, the Immature Platelet Fraction and the Immature Platelet Fraction Count, in dengue patients

Autor: Rontgene M. Solante, Chris Fook Sheng Ng, Nobuo Koizumi, Koya Ariyoshi, Ikkoh Yasuda, Ferdinand De Guzman, Michio Yasunami, Motoi Suzuki, Emi Kitashoji, Kentaro Sakashita, Dorcas Valencia Umipig, Nobuo Saito, Chris Smith, Ana Ria Sayo
Rok vydání: 2021
Předmět:
Male
Bacterial Diseases
Viral Diseases
Time Factors
Physiology
Nosocomial Infections
Immature Platelet
Dengue fever
Dengue Fever
Dengue
Medical Conditions
Animal Cells
Medicine and Health Sciences
Platelet
Multidisciplinary
medicine.diagnostic_test
Complete blood count
Bacterial Infections
Hematology
respiratory system
Body Fluids
Community-Acquired Infections
Hospitalization
Blood
Infectious Diseases
Medicine
Female
Anatomy
Cellular Types
Research Article
Neglected Tropical Diseases
Blood Platelets
Platelets
medicine.medical_specialty
Science
Young Adult
Hematologic disorders
Diagnostic Medicine
Internal medicine
medicine
Humans
In patient
Blood Cells
business.industry
Platelet Count
Significant difference
Biology and Life Sciences
Cell Biology
medicine.disease
Tropical Diseases
Thrombocytopenia
respiratory tract diseases
Blood Cell Count
Time course
business
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0258936 (2021)
ISSN: 1932-6203
Popis: The advanced platelet parameters Immature Platelet Fraction and Immature Platelet Fraction Count have been implemented in clinical practice as measures of thrombopoietic activity, mainly in hematologic disorders that cause thrombocytopenia. The purpose of this observational study was to examine thrombopoiesis as reflected by these 2 new CBC parameters in patients infected with dengue. The study was conducted in infectious disease referral hospital in Metro Manila, the Philippines. We enrolled hospitalized patients at admission who were diagnosed with acute dengue or community acquired bacterial infection (CABI). Immature Platelet Fraction (IPF) and Immature Platelet Fraction Count were evaluated at admission and during hospitalization. A total of 606 patients were enrolled from May 1, 2017 to June 1, 2018. The participants consisted of 152 patients with dengue infection, 180 confirmed CABI, and 274 suspected CABI patients. At admission, the percent IPF (IPF%) of the patients with dengue was significantly higher than that of the confirmed CABI patients (median 3.7% versus 1.9%; p
PLoS ONE, 16, art. no. e0258936; 2021
Databáze: OpenAIRE
Externí odkaz: