Chemical Aspects of Human and Environmental Overload with Fluorine
| Autor: | Loránd Kiss, Daniel M. Sedgwick, Jianlin Han, Vadim A. Soloshonok, Hiroki Moriwaki, Haibo Mei, Santos Fustero, Raquel Román, Maja Ponikvar-Svet, Attila Márió Remete |
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| Rok vydání: | 2021 |
| Předmět: |
Hydrocarbons
Fluorinated 010405 organic chemistry Chemistry Agrochemical business.industry chemistry.chemical_element Química farmacèutica Fluorine General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences Fluoride intake chemistry.chemical_compound Human health Fluorochemical industry Environmental chemistry Inorganic fluorine compounds Environmental Pollutants Pèptids Organofluorine compounds Environmental Pollution business Fluoride |
| Zdroj: | Han, Jianlin Kiss, Loránd Mei, Haibo Remete, Attila Márió Ponikvar-Svet, Maja Sedgwick, Daniel Mark Roman, Raquel Fustero Lardiés, Santos Moriwaki, Hiroki Soloshonok, Vadim A. 2021 Chemical aspects of human and environmental overload with fluorine Chemical Reviews 121 8 4678 4742 RODERIC. Repositorio Institucional de la Universitat de Valéncia instname |
| ISSN: | 1520-6890 0009-2665 |
| DOI: | 10.1021/acs.chemrev.0c01263 |
| Popis: | Over the last 100-120 years, due to the ever-increasing importance of fluorine-containing compounds in modern technology and daily life, the explosive development of the fluorochemical industry led to an enormous increase of emission of fluoride ions into the biosphere. This made it more and more important to understand the biological activities, metabolism, degradation, and possible environmental hazards of such substances. This comprehensive and critical review focuses on the effects of fluoride ions and organofluorine compounds (mainly pharmaceuticals and agrochemicals) on human health and the environment. To give a better overview, various connected topics are also discussed: reasons and trends of the advance of fluorine-containing pharmaceuticals and agrochemicals, metabolism of fluorinated drugs, withdrawn fluorinated drugs, natural sources of organic and inorganic fluorine compounds in the environment (including the biosphere), sources of fluoride intake, and finally biomarkers of fluoride exposure. |
| Databáze: | OpenAIRE |
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