Autor: |
Yamuna Devi Bakthavatchalam, Soumya Basu, Abirami Shankar, Sudha Ramaiah, Anand Anbarasu, Balaji Veeraraghavan |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Diagnostic Microbiology and Infectious Disease. 105:115878 |
ISSN: |
0732-8893 |
Popis: |
The present study reported a rare gentamicin-susceptible β-lactamase (PenA, OXA-57) expressing clinical Burkholderia pseudomallei isolate VB29710 from India. Whole-genome sequencing and structural analyses revealed the insertion of R962 and L963 into AmrB, the transmembrane-protein of the AmrAB-OprA efflux-pump that affected aminoglycoside-efflux through local alterations in backbone conformation. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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