Comparison of long-term incidence of posterior capsular opacification between phacoemulsification and phacotrabeculectomy
| Autor: | Steven Y Reed, Scott M Vandenbelt, Paul H Kim, Dong H. Shin, Jason P. Gross, Catherine M Birt, Sang H Lee, Nandita S Keole |
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| Rok vydání: | 2002 |
| Předmět: |
Male
Michigan medicine.medical_specialty Intraocular pressure Visual acuity genetic structures Antimetabolites Mitomycin medicine.medical_treatment Lens Capsule Crystalline Visual Acuity Glaucoma Trabeculectomy Intraocular lens Cataract Lens Implantation Intraocular Ophthalmology medicine Humans Longitudinal Studies Intraocular Pressure Aged Retrospective Studies Phacoemulsification business.industry Incidence Mitomycin C medicine.disease eye diseases Surgery Case-Control Studies Capsulotomy Female sense organs medicine.symptom business Glaucoma Open-Angle |
| Zdroj: | American Journal of Ophthalmology. 133:40-47 |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/s0002-9394(01)01285-5 |
| Popis: | PURPOSE: To investigate the long-term incidence of posterior capsular opacification after phacoemulsification compared with phacotrabeculectomy with or without adjunctive subconjunctival mitomycin C. METHODS: This was a retrospectively conducted long-term, observational, case-control study. One hundred eyes of 100 cataract patients who underwent phacoemulsification and posterior chamber intraocular lens implantation and 100 eyes of 100 primary open-angle glaucoma patients with cataract that underwent phacotrabeculectomy and posterior chamber intraocular lens implantation, matched with respect to age, intraocular lens type, prevalence of diabetes mellitus, and length of follow-up. The main outcome measure was the rate of clinically significant posterior capsular opacification as determined by slit-lamp biomicroscopy and necessity to perform neodynium:yttrium aluminum garnet (Nd:YAG) capsulotomy and as calculated by Kaplan-Meier survival analysis. Postoperative visual acuity and maintenance of intraocular pressure control were also measured. RESULTS: There was no significant difference in the rate of posterior capsular opacification requiring Nd:YAG capsulotomy between the phacoemulsification and phacotrabeculectomy groups ( P = .77). However, a significant difference in the rate of posterior capsular opacification was found between those patients without diabetes mellitus and those with a preoperative diagnosis of diabetes mellitus ( P = .016). Also, survival analysis comparing use of mitomycin C with no use of mitomycin C in the phacotrabeculectomy group showed a higher survival in the mitomycin C subgroup ( P = .03). CONCLUSION: There was no significant difference in long-term posterior capsular opacification between phacoemulsification and phacotrabeculectomy in the study population. Intraoperative, adjunctive use of mitomycin C in the phacotrabeculectomy group and the presence of diabetes mellitus in the overall patients were beneficial (protective) factors against posterior capsular opacification. |
| Databáze: | OpenAIRE |
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