Immunostimulating hexapeptide from human casein: amino acid sequence, synthesis and biological properties
| Autor: | Jacqueline Jollès, Fabienne Parker, Daniele Migliore-Samour, Monika Casaretto, G. H. Werner, Aurelio Zerial, Pierre Jollès, H. Zahn, F. Floc'h |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Erythrocytes Chemical Phenomena medicine.drug_class Klebsiella pneumoniae Phagocytosis Peptide Biology Biochemistry Immunostimulant Mice Adjuvants Immunologic Casein medicine Animals Humans Amino Acid Sequence Amino Acids Peptide sequence Opsonin chemistry.chemical_classification Sheep biology.organism_classification In vitro Klebsiella Infections Chemistry chemistry Mice Inbred CBA Female Oligopeptides |
| Zdroj: | European Journal of Biochemistry. 145:677-682 |
| ISSN: | 1432-1033 0014-2956 |
| DOI: | 10.1111/j.1432-1033.1984.tb08609.x |
| Popis: | A hexapeptide obtained from human casein by enzymatic digestion has been purified, sequenced and synthesized; its structure is: Val-Glu-Pro-Ile-Pro-Tyr. In vitro this hexapeptide stimulates the phagocytosis of opsonized sheep red blood cells by murine peritoneal macrophages. Administered intravenously to adult mice, it enhances the resistance to infection with Klebsiella pneumoniae. |
| Databáze: | OpenAIRE |
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