Megavoltage conebeam CT cine as final verification of treatment plan in lung stereotactic body radiotherapy
| Autor: | Athanasios Colonias, Olivier Gayou, V. Kudithipudi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Lung Neoplasms medicine.medical_treatment Planning target volume Computed tomography 4D Computed Tomography urologic and male genital diseases 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Treatment plan Carcinoma Non-Small-Cell Lung Humans Medicine Dosimetry Radiology Nuclear Medicine and imaging Four-Dimensional Computed Tomography medicine.diagnostic_test business.industry Radiotherapy Planning Computer-Assisted Ptv margin Cone-Beam Computed Tomography Radiation therapy Oncology 030220 oncology & carcinogenesis Radiology business Nuclear medicine Stereotactic body radiotherapy |
| Zdroj: | Journal of Medical Imaging and Radiation Oncology. 60:441-445 |
| ISSN: | 1754-9477 |
| Popis: | Introduction To analyse the clinical impact of megavoltage conebeam computed tomography (MV-CBCT) cine on internal target volume (ITV) coverage in lung stereotactic body radiotherapy (SBRT). Methods One hundred and six patients received lung SBRT. All underwent 4D computed tomography simulation followed by treatment via image guided 3D conformal or intensity modulated radiation. Prior to SBRT, all patients underwent MV-CBCT cine, in which raw projections are displayed as beam's-eye-view fluoroscopic series with the planning target volume (PTV) projected onto each image, enabling verification of tumour motion relative to the PTV and assessment of adequacy of treatment margin. Results Megavoltage conebeam computed tomography cine was completed 1–2 days prior to SBRT. Four patients (3.8%) had insufficient ITV coverage inferiorly at cine review. All four plans were changed by adding 5 mm on the PTV margin inferiorly. The mean change in PTV volumes was 3.9 cubic centimetres (cc) (range 1.85–6.32 cc). Repeat cine was performed after plan modification to ensure adequate PTV coverage in the modified plans. Conclusions PTV margin was adequate in the majority of patients with this technique. MV-CBCT cine did show insufficient coverage in a small subset of patients. Insufficient PTV margins may be a function of 4D CT simulation inadequacies or deficiencies in visualizing the ITV inferior border in the full-inhale phase. MV-CBCT cine is a valuable tool for final verification of PTV margins. |
| Databáze: | OpenAIRE |
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