Aqueous multiphoton lithography with multifunctional silk-centred bio-resists
| Autor: | Si-Ming Sun, Qi Li, Zhengzhong Shao, Hong-Bo Sun, Yun-Lu Sun, Qi-Dai Chen, Jingchun Huang, Bo-Yuan Zheng |
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| Rok vydání: | 2015 |
| Předmět: |
Silver
Multidisciplinary Nanostructure Materials science Lasers General Physics and Astronomy Fibroin Biomaterial Nanotechnology General Chemistry Bombyx Multiphoton lithography Article General Biochemistry Genetics and Molecular Biology Nanostructures SILK Nanolithography Resist Spectroscopy Fourier Transform Infrared Animals Gold Fibroins Nanoscopic scale |
| Zdroj: | Nature Communications |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/ncomms9612 |
| Popis: | Silk and silk fibroin, the biomaterial from nature, nowadays are being widely utilized in many cutting-edge micro/nanodevices/systems via advanced micro/nanofabrication techniques. Herein, for the first time to our knowledge, we report aqueous multiphoton lithography of diversiform-regenerated-silk-fibroin-centric inks using noncontact and maskless femtosecond laser direct writing (FsLDW). Initially, silk fibroin was FsLDW-crosslinked into arbitrary two/three-dimensional micro/nanostructures with good elastic properties merely using proper photosensitizers. More interestingly, silk/metal composite micro/nanodevices with multidimension-controllable metal content can be FsLDW-customized through laser-induced simultaneous fibroin oxidation/crosslinking and metal photoreduction using the simplest silk/Ag+ or silk/[AuCl4]− aqueous resists. Noticeably, during FsLDW, fibroin functions as biological reductant and matrix, while metal ions act as the oxidant. A FsLDW-fabricated prototyping silk/Ag microelectrode exhibited 104-Ω−1 m−1-scale adjustable electric conductivity. This work not only provides a powerful development to silk micro/nanoprocessing techniques but also creates a novel way to fabricate multifunctional metal/biomacromolecule complex micro/nanodevices for applications such as micro/nanoscale mechanical and electrical bioengineering and biosystems. Scientists are increasingly realising the potential for natural materials in micro- and nanofabrication. Here, the authors employ silk-based resists for aqueous multiphoton lithography towards generating intricate structures by femtosecond direct writing. |
| Databáze: | OpenAIRE |
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